Liporen
Description:
Liposomal iron, a new generation oral iron with high gastrointestinal absorption and bioavailability and a low incidence of side effects, a promising new strategy of iron replacement.Top of Form
Iron supplementation is essential for the treatment of anemia in the chronic kidney disease (CKD) population. Liporen contains Liposomal Ferric Pyrophosphate with Vitamin C, Vitamin B6 and Methylcobalamin. Liporen is a formulation of Liposomal iron ferric pyrophosphate carried within a phospholipidic membrane. Compared to other oral formulations, it is well absorbed from the gut and demonstrates high bioavailability together with a lower incidence of side effects.
Category: Renal Anemia
Indications
Liporen (Liposomal Ferric Pyrophosphate) is indicated for the treatment of iron loss or iron deficiency anemia of different etiologies.
Composition
Liposomal Ferric Pyrophosphate 30mg + Vitamin C 50 mg + Vitamin B12 0.75 mcg + Folic acid 300 mcg
Mechanism of action:
Ferric pyrophosphate works by:
- Forming a strong complex with other species
- Triggering iron removal from transferrin
- Enhancing iron transfer from transferrin to ferritin
- Promoting iron exchange between transferrin molecules
Liposomal iron is absorbed into the intestinal lumen by microfold cells (M cells) in the small intestine. The liposome is then incorporated into macrophages by endocytosis and reaches hepatocytes through the lymphatic system
Purpose
Iron Supplementation: Liposomal ferric pyrophosphate is a source of elemental iron, an essential component for the production of hemoglobin in red blood cells.
Liposomal Delivery: Liposomes are small vesicles made of lipids that can encapsulate and deliver substances, in this case, iron. The liposomal delivery system is designed to enhance the absorption of iron in the gastrointestinal tract.
Avoiding Gastrointestinal Side Effects: Traditional iron supplements can cause gastrointestinal side effects such as constipation or stomach upset. Liposomal formulations aim to minimize these side effects by improving iron absorption in the intestines
Treatment of Iron Deficiency Anemia: Liposomal ferric pyrophosphate is prescribed for individuals with iron deficiency anemia, including those who cannot tolerate other forms of oral iron supplements due to gastrointestinal issue
Dosage:
1 Capsule OD or as directed by the healthcare professional.
Presentation:
One carton contains 1 strip of 10 Capsules each.
Disclaimer
This information is for registered medical practitioner only. All others should consult a medical practitioner before using it
