Prumia Gel
Relief for Uremic Pruritus in CKD Patients
Uremic pruritus affects over 60% of CKD and dialysis patients, often robbing them of restful sleep, peace of mind, and dignity. Traditional treatments—oral medications, antihistamines, or emollients—often fail or come with systemic side effects.
Prumia™ gel is a topical, triple-action formulation designed to safely relieve pruritus right at its source.
Category: Renal Medicine
Formulation Highlights
| Active Ingredient | Function |
| Gabapentin 6% | Modulates peripheral nerve hypersensitivity |
| Lidocaine 5% | Rapid local anesthetic for itch relief |
| Aloe Vera Gel Base | Soothes and hydrates CKD-damaged skin |
| Methylparaben + Propylparaben | Stabilizes the formula safely |
Mechanism of Action
Gabapentin 6%
Targets abnormal peripheral nerve activity and central sensitization, reducing chronic neuropathic itch common in CKD.
Lidocaine 5%
Delivers fast-acting local anesthesia by blocking sodium channels—offering near-immediate relief from discomfort.
Aloe Vera
Well studied for it’s anti-pruritic actions in addition also Rebuilds skin moisture barrier, calms inflammation, and restores skin resilience.
- Ideal for Nocturnal Itch
- Non-systemic – No burden on kidneys
- No fluid intake, sugar, or taste issues
- Non-greasy, fast-absorbing gel
- Steroid-free and opioid-free
Recent studies support the topical use of gabapentinoids and lidocaine for neuropathic and uremic pruritus with:
- Significant reduction in itch scores
- Improved sleep and quality of life
- High tolerability in dialysis and elderly patients
Suited for Pruritus in
- CKD Stage 4–5
- Hemodialysis and peritoneal dialysis patients
- Elderly patients
- Patients intolerant to systemic therapies
- Palliative care / refractory pruritus cases
How to Use
- Apply thin layer over affected area
- Use 3-4 times daily or as directed
- For external use only; avoid eyes and broken skin
Available in:
- 30 g tubes
- Dermatologically safe
- Prescription-based use
